Perceptions on the management, exposure, biosafety and handling of cytostatics in the nursing staff of a private health institution in the Autonomous City of Buenos Aires
DOI:
https://doi.org/10.4321/s0465-546x2022000200004Keywords:
Antineoplastics, Cytostatics, Nursing, Nursing Care, Oncology Nursing, Occupational Risks, Organizational Culture, Biosecurity, Professional CancerAbstract
Introduction: The oncology nurse practitioner is trained with knowledge about cancer, treatment modalities, patient care scenarios. The risk to exposure resulting from handling cytostatics can affect the health of healthcare workers. Objective: to describe the biosafety measures for handling cytostatics and the clinical signs and symptoms resulting from exposure to these drugs in the nursing staff of a private health care institution in the Autonomous City of Buenos Aires.
Methods: An observational, descriptive, retrospective, cross-sectional, retrospective study was carried out. The sample consisted of 31 nursing professionals. The data collection instrument used was the one proposed by Villa and Varela-Díaz (2020), which records sociodemographic, occupational, health and biosafety measures data.
Results: The sample was 74.2% female, the average age was 37.67±6.79, 58.1% had a Bachelor’s degree in Nursing, with an average experience in oncology of 4.06±4.09. Of the participants, 96.8% administered cytostatics and 51.6% were involved in disposal. The main symptoms reported were headache and abdominal pain with 64.5% and 45.2% respectively. 41.9% referred to paraclinical examinations and control by the institution.
Conclusions: Nursing personnel are exposed to high occupational risks when dealing with cytostatics. Compliance with protocols for handling and disposal is required in order to raise patient safety and occupational safety standards.
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Mesa Rincón NM, Martín Fuentes AM, Martín Fuentes AM, Papagayo Guzmán ML. Competencias en enfermería oncológica para educar al paciente en quimioterapia [Internet] [Tesis de Especialidad]. [Bogotá]: Universidad del Bosque; 2020 [citado 9 de abril de 2022]. Disponible en: https://repositorio.unbosque.edu.co/handle/20.500.12495/3964
Lesage C, Guillot B, Sibaud V. Toxicidad cutánea de la quimioterapia del cáncer. EMC - Dermatología. 2020;54(4):1-18.
Eu Marcela DF, Eu Sylvia GN, Eu Juan Carlos LC, Eu Aracely TM. Enfermería oncológica: estándares de seguridad en el manejo del paciente oncológico. Revista Médica Clínica Las Condes. 2013;24(4):694-704.
Ruda CAR. Toxicidad hematológica de la quimioterapia. Revisiones en cáncer. 2019;33(3):1-10.
Clerencia Casado I. Efectos de la manipulación de los fármacos citostáticos en el personal sanitario [Internet] [Tesis de Grado]. [País Vasco]: Universidad del País Vasco; 2018 [citado 9 de abril de 2022]. Disponible en: https://addi.ehu.es/handle/10810/30372
Montero HMR, Reyes ER, Leyva TME, Aguila RC, Torres A, Valle EB. Monitoreo de seguridad ocupacional en el manejo de citostáticos. Journal of Pharmacy & Pharmacognosy Research. 2018;6(6):433-47.
Falces Castillo P, Gasch Gallén Á. Protocolo de enfermería para el manejo seguro de medicamentos citostáticos [Internet] [Tesis de Grado]. [Zaragoza]: Universidad de Zaragoza; 2021. Disponible en: https://zaguan.unizar.es/record/107223
Niccolini MA. Administración y manipulación de citostáticos del personal de enfermería en Salas de Oncología, en Hospital de dependencia provincial y Efector privado de la Ciudad de Rosario. Año 2021 [Internet] [Tesis de Grado]. [Rosario]: Universidad Nacional del Rosario; 2020 [citado 9 de abril de 2022]. Disponible en: http://rephip.unr.edu.ar/xmlui/handle/2133/21750
Villa MP, Varela-Díaz V. Medidas de bioseguridad en la manipulación de medicamentos citotóxicos y signos y síntomas de la exposición al riesgo en el personal de enfermería. Revista Salud Bosque. 2020;10(1):32-40.
Farroñán-Sondor RE, Serquén-López LM. Ensayo cometa: una prueba necesaria para la detección de genotoxicidad en profesionales de la salud. Revista Experiencia en Medicina del Hospital Regional Lambayeque. 2019;5(3):146-7.
Suspiro A, Prista J. Occupational exposure to anticancer drugs and adverse health effects. Revista Portuguesa de Saúde Pública. 2012;30(1):76-88.
Simegn W, Dagnew B, Dagne H. Knowledge and associated factors towards cytotoxic drug handling among University of Gondar Comprehensive Specialized Hospital health professionals, institutional-based cross-sectional study. Environmental Health and Preventive Medicine. 2020;25:11.
Habiba A, Eldin YKZ, Ibrahem EM. Oncology nurses’ knowledge andpractices regarding handling hazardous drugs: developing procedure manual for safe handling Of hazardous drugs. IOSR Journal of Nursing and Health Science (IOSR-JNHS). 2018;7(2):1-11.
Zyoud SH, Khaled SM, Kawasmi BM, Habeba AM, Hamadneh AT, Anabosi HH, et al. Knowledge about the administration and regulation of high alert medications among nurses in Palestine: a cross-sectional study. BMC Nurs. 2019;18(1):11.
Hori A, Shimura M, Iida Y, Yamada K, Nohara K, Ichinose T, et al. Occupational exposure of platinum-based anti-cancer drugs: five-year monitoring of hair and environmental samples in a single hospital. J Occup Med Toxicol. 2020;15:29.
Rekhadevi PV, Sailaja N, Chandrasekhar M, Mahboob M, Rahman MF, Grover P. Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs. Mutagenesis. 2007;22(6):395-401.
Krstev S, Perunicić B, Vidaković A. Work practice and some adverse health effects in nurses handling antineoplastic drugs. Med Lav. 2003;94(5):432-9.
Oltulu C, Devecioglu TY, Akinci M, Olmez SGA, OBEİDİN SV, Beceren A. Evaluation of Genotoxicity Risk in Health Care Workers Exposed to Antineoplastic Drugs. Clinical and Experimental Health Sciences. 2019;9(2):166-70.
El-Ebiary AA, Abuelfadl AA, Sarhan NI. Evaluation of genotoxicity induced by exposure to antineoplastic drugs in lymphocytes of oncology nurses and pharmacists. J Appl Toxicol. 2013;33(3):196-201.
Rodriguez Montero HM, Reyes Reyes E, Escalante Leyva TM, Correa Aguila R, Torres Valle A, Cuetara-Lugo EB. Safety monitoring of cytostatic handling. J Pharm Pharmacogn Res. 2018;6(6):433-47.
Alvarado Aurora EA, Flores Malca ME. Nivel de conocimientos en el manejo de citostásticos y actitudes de bioseguridad en las enfermeras Hospital Víctor Lazarte Echegaray 2012 [Internet] [Tesis de Grado]. [La Libertad]: Universidad Nacional de Trujillo; 2012 [citado 30 de abril de 2022]. Disponible en: http://dspace.unitru.edu.pe/handle/UNITRU/13958
Barrionuevo Hijar JL. Conocimiento y actitud sobre medidas de bioseguridad en el manejo de agentes citostáticos por el personal sanitario de una clínica, Lima 2021 [Internet] [Tesis de Maestría]. [Lima]: Universidad Cesar Vallejo; 2022 [citado 30 de abril de 2022]. Disponible en: https://repositorio.ucv.edu.pe/handle/20.500.12692/84075
HA Z, SM S, RM ES, WM S. Knowledge, attitudes and practices of safe handling of cytotoxic drugs among oncology nurses in tanta university hospitals. Egyptian Journal of Occupational Medicine. 2019;43(1):75-92.
Ha Z, Sm S, Rm ES, Wm S. Knowledge, attitudes and practices of safe handling of cytotoxic drugs among oncology nurses in tanta university hospitals. Egyptian Journal of Occupational Medicine. 2019;43(1):75-92.
Yu E. Occupational Exposure in Health Care Personnel to Antineoplastic Drugs and Initiation of Safe Handling in Hong Kong: A Literature Review. J Infus Nurs. 2020;43(3):121-33.
Torres-Contreras C, Buitrago-Vera M. Percepción de la calidad del cuidado de enfermería en pacientes oncológicos hospitalizados. Revista Cuidarte. 2011;2(1):138-48.
Karadağ A, Hisar F, Elbaş NÖ. The Level of Professionalism Among Nurses in Turkey. Journal of Nursing Scholarship. 2007;39(4):371-4.
Tanaka M, Yonemitsu Y, Kawamoto R. Nursing professionalism: A national survey of professionalism among Japanese nurses. International Journal of Nursing Practice. 2014;20(6):579-87.
Bates M, Bautista A. La educación continua y la capacitación del profesional de enfermería. Revista Mexicana de Enfermería Cardiológica. 2008;16(3):115-7.
Luengo-Martínez C, Paravic-Klijn T, Burgos-Moreno M, Luengo-Martínez C, Paravic-Klijn T, Burgos-Moreno M. Profesionalismo en enfermería: una revisión de la literatura. Enfermería universitaria. 2017;14(2):131-42.
Clark C. How can we protect cancer nurses from exposure to hazardous drugs? Br J Nurs. 2021;30(4):S16-20.
Wiszniewska M, Książek A, Lipińska-Ojrzanowska A, Walusiak-Skorupa J. Occupational exposure to cytostatic fumes during hyperthermic intraperitoneal chemotherapy. Occup Med (Lond). 2020;70(4):286-8.
Gomes PMM, Nascimento ND do, Paes GO. The disposal of chemical-pharmacological waste in hospitalization units. Revista de Pesquisa Cuidado é Fundamental Online. 2021;13:192-6.
Amo MP, Parra AQ, Pino AP. Rol de enfermería en pacientes oncológicos. En: Avances de Investigación en Salud a lo largo del Ciclo Vital: Volumen II [Internet]. Almería: Asociación Universitaria de Educación y Psicología (ASUNIVEP); 2018 [citado 30 de abril de 2022]. p. 223-7. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=6806921
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