New HIV diagnoses among people aged 50 years and over in Spain, 2013-2022

Authors

DOI:

https://doi.org/10.4321/s2173-92772024000100002

Keywords:

HIV infection, people aged 50 or older, late diagnoses, surveillance

Abstract

Introduction: Among the older population with human immunodeficiency virus (HIV) infection are those who acquired the infection in previous decades as well as those who are currently diagnosed at 50 years of age or older. The aim of this paper is to describe the characteristics of new HIV diagnoses identified in Spain in 2022 from people aged 50 years or older, and to analyse their trend between 2013-2022.

Method: Descriptive study of new diagnoses aged 50 years or older reported to the Surveillance System for New HIV Diagnoses (2013-2022) and their comparison with those aged 15-49 years. Trends were studied through rate variation.

Results: In 2022, there were 2,952 new HIV diagnoses in people over 14 years of age, of which 18.3% (540) were 50 years of age or older. The majority were men (84.3%), born in Spain (68.7%), and the most frequent transmission mode was unprotected sexual relations between men (40.7%). 64.4% of total cases had late diagnosis. Compared with cases aged 15-49, a higher proportion of Spaniards, heterosexual men, and cases with delayed diagnosis were observed. Among those 50 years of age or older, rate trends, overall, by sex and mode of transmission, were downward mainly between 2019 and 2020. The percentage of cases with late diagnosis did not change along the period.

Conclusions: The high proportion of late diagnosis in new diagnoses of older age makes it necessary to reinforce primary and secondary prevention in this group of population.

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References

The path that ends AIDS: UNAIDS Global AIDS Update 2023. Geneva: Joint United Nations Programme on HIV/AIDS; 2023. [Internet]. Disponible en: https://thepath.unaids.org/

Tavoschi L, Gomes Dias J, Pharris A, EU/EEA HIV Surveillance Network. New HIV diagnoses among adults aged 50 years or older in 31 European countries, 2004-15: an analysis of surveillance data. Lancet HIV. noviembre de 2017;4(11):e514-21.

European Centre for Disease Prevention and Control/WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2023 – 2022 data. Stockholm: ECDC; 2023.

Poynten IM, Grulich AE, Templeton DJ. Sexually transmitted infections in older populations. Curr Opin Infect Dis. febrero de 2013;26(1):80-5.

INSIGHT START Study Group, Lundgren JD, Babiker AG, Gordin F, Emery S, Grund B, et al. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. N Engl J Med. 27 de agosto de 2015;373(9):795-807.

Antinori A, Coenen T, Costagiola D, Dedes N, Ellefson M, Gatell J, et al. Late presentation of HIV infection: a consensus definition. HIV Med. enero de 2011;12(1):61-4.

Late Presentation Working Groups in EuroSIDA and COHERE. Estimating the burden of HIV late presentation and its attributable morbidity and mortality across Europe 2010-2016. BMC Infect Dis. 7 de octubre de 2020;20(1):728.

Autenrieth CS, Beck EJ, Stelzle D, Mallouris C, Mahy M, Ghys P. Global and regional trends of people living with HIV aged 50 and over: Estimates and projections for 2000-2020. PLoS One. 2018;13(11):e0207005.

Sánchez-Conde M, Díaz-Alvarez J, Dronda F, Brañas F. Why are people with HIV considered «older adults» in their fifties? Eur Geriatr Med. abril de 2019;10(2):183-8.

Blanco JR, Jarrín I, Vallejo M, Berenguer J, Solera C, Rubio R, et al. Definition of advanced age in HIV infection: looking for an age cut-off. AIDS Res Hum Retroviruses. septiembre de 2012;28(9):1000-6.

Brañas F, Jiménez Z, Sánchez-Conde M, Dronda F, López-Bernaldo De Quirós JC, Pérez-Elías MJ, et al. Frailty and physical function in older HIV-infected adults. Age Ageing. 1 de mayo de 2017;46(3):522-6.

Encuesta Hospitalaria de pacientes con infección por el VIH. Resultados 2023. Análisis de la evolución 2008-2023. Centro Nacional de Epidemiología-Instituto de Salud Carlos III / División de control de VIH, ITS, Hepatitis virales y Tuberculosis. Ministerio de Sanidad. Madrid; noviembre 2023. [Internet]. 2023. Disponible en: https://www.isciii.es/QueHacemos/Servicios/VigilanciaSaludPublicaRENAVE/EnfermedadesTransmisibles/Documents/VIH/informes%20encuesta%20hospitalaria%20anteriores/Informe%20Encuesta%20hospitalaria_2008_2023.pdf

Unidad de vigilancia de VIH, ITS y hepatitis. Vigilancia Epidemiológica del VIH y sida en España 2022: Sistema de Información sobre Nuevos Diagnósticos de VIH y Registro Nacional de Casos de Sida. Centro Nacional de Epidemiología. Instituto de Salud Carlos III/ División de control de VIH, ITS, Hepatitis virales y tuberculosis. Ministerio de Sanidad. Madrid; noviembre 2023. [Internet]. 2023. Disponible en: https://www.isciii.es/QueHacemos/Servicios/VigilanciaSaludPublicaRENAVE/EnfermedadesTransmisibles/Documents/VIH/informes%20de%20vigilancia%20VIH%20y%20sida%20anteriores/Informe%20VIH_SIDA_2023_Nov%202023.pdf

Youssef E, Cooper V, Delpech V, Davies K, Wright J. Barriers and facilitators to HIV testing in people age 50 and above: a systematic review. Clin Med (Lond). diciembre de 2017;17(6):508-20.

Centers for Disease Control and Prevention. Estimated HIV incidence and prevalence in the United States, 2015–2019. HIV Surveillance Supplemental Report 2021;26(No. 1). http://www.cdc.gov/ hiv/library/reports/hiv-surveillance.html. Published May 2021. [Internet]. [citado 5 de febrero de 2024]. Disponible en: http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html

Unidad de vigilancia de VIH, ITS y hepatitis B y C. Vigilancia epidemiológica de las infecciones de transmisión sexual, 2022. Centro Nacional de Epidemiología, Instituto de Salud Carlos III/División de Control de VIH, ITS, Hepatitis virales y Tuberculosis, Dirección General de Salud Pública; 2024. Disponible en: https://www.isciii.es/QueHacemos/Servicios/VigilanciaSaludPublicaRENAVE/EnfermedadesTransmisibles/Documents/archivos%20A-Z/SIFILIS/Informe_Vigilancia_ITS_2022.pdf.

Justice AC, Goetz MB, Stewart CN, Hogan BC, Humes E, Luz PM, et al. Delayed presentation of HIV among older individuals: a growing problem. Lancet HIV. abril de 2022;9(4):e269-80.

Moreno S, Mocroft A, Monforte A d’Arminio. Medical and societal consequences of late presentation. Antivir Ther. 2010;15 Suppl 1:9-15.

Rava M, Domínguez-Domínguez L, Bisbal O, López-Cortés LF, Busca C, Antela A, et al. Late presentation for HIV remains a major health issue in Spain: Results from a multicenter cohort study, 2004-2018. PLoS One. 2021;16(4):e0249864.

Hall HI, Holtgrave DR, Tang T, Rhodes P. HIV transmission in the United States: considerations of viral load, risk behavior, and health disparities. AIDS Behav. junio de 2013;17(5):1632-6.

Oraka E, Mason S, Xia M. Too old to test? Prevalence and correlates of HIV testing among sexually active older adults. J Gerontol Soc Work. 2018;61(4):460-70.

Brown MJ, Adeagbo O. HIV and Aging: Double Stigma. Curr Epidemiol Rep. 2021;8(2):72-8.

UNAIDS. People Aged 50 years and older. The Gap Report 2014 [Internet]. 2014. Report No.: UNAIDS / JC2656. Disponible en: https://www.unaids.org/sites/default/files/media_asset/12_Peopleaged50yearsandolder.pdf

Documento de consenso sobre envejecimiento en las personas con infección por el virus de la inmunodeficiencia humana. Actualización 2021 [Internet]. Disponible en: https://www.sanidad.gob.es/ciudadanos/enfLesiones/enfTransmisibles/sida/documentos/110521_Doc_CONSENSO_ENVEJECIMIENTO_Y_VIH.pdf

Hernando Sebastián V, Ruiz-Algueró M, Simón Mendez L, Diaz Franco A. Impacto de la pandemia de la COVID-19 en los sistemas de vigilancia epidemiológica de la infección por VIH en España. Rev Esp Salud Pública. 2023; 97: e202311093.

De la Torre-Lima J, Oteo JA, Pinilla J, Mansilla R, Zamora C, Ayala Vargas V, et al. Study on the approach to HIV: health management and the healthcare process in Spain. Enferm Infecc Microbiol Clin (Engl Ed). diciembre de 2023;41(10):604-11.

Published

2024-05-06

How to Cite

1.
Diaz A, Simón L, Villegas-Moreno T, Hernando V. New HIV diagnoses among people aged 50 years and over in Spain, 2013-2022. BES [Internet]. 2024 May 6 [cited 2024 Nov. 21];32(1):10-2. Available from: //revista.isciii.es/index.php/bes/article/view/1356

Issue

Section

Estudios Epidemiológicos